This application note describes a method using the Varian 220-MS ion trap mass spectrometer (Figure 2) to determine melamine and its analogs qualitatively and quantitatively based on the framework of the original FDA method.
This document details a method developed to determine melamine, ammeline, ammelide, and cyanuric acid in infant milk-based formula and other food/feed products. The method utilizes the Varian 220-MS ion trap mass spectrometer coupled with a gas chromatograph and V:Results software to perform qualitative and quantitative analysis.
| Column | FactorFour VF-Xms, 30 m x 0.25 mm x 0.25 pm |
|---|---|
| Inlet Temperature | 280 °C |
| Carrier Gas Flow | Helium at 1 mL/min |
| Trap Temp | 220 °C |
| Detection Limit | below 10 ppb |
The method detects melamine, cyanuric acid, ammelide, and ammeline.
The analysis is performed using V:Results GC/MS software.