Agilent G1978B Multimode Source for 6510 Q-TOF LC/MS User Guide

This manual provides an introduction to the Agilent G1978B Multimode Source. It covers the source's components, installation and setup, operation, and maintenance.


Agilent G1978B Multimode Source for 6510 Q-TOF LC/MS User Guide - cover page
Brand
Agilent
Document type
User Manual
Language
English
Pages
62
File format
PDF
File size
1.3 MB
Published
07 June, 2012
Updated
30 September, 2023
Model
G1978B
MD5 checksum
C1D1574B9FE2A86DED4740513A04A54F

About this manual

This user guide provides instructions for installing, operating, maintaining, and troubleshooting the Agilent G1978B multimode ion source for the 6510 Q-TOF LC/MS system. It includes setup procedures, safety precautions, technical specifications, and guidelines for ionization modes such as ESI, APCI, and mixed modes. The guide also covers daily and weekly cleaning routines, tuning procedures, and method configuration using MassHunter software.

The document is structured into sections covering basic operation, installation steps, reference material including safety symbols and technical specs, and empirical formulas for high-resolution MS calibration.

What's inside

  • Basic Operation and Maintenance
  • Installation
  • Reference
  • Safety and Specifications
  • Overview
  • Guidelines for Ionization Modes
  • Tuning Mix and Test Mix
  • ESI Calibration Ions
  • APCI Calibration Ions

Specifications

Model NumberG1978B
Product TypeMultimode Ion Source
Compatible System6510 Q-TOF LC/MS
Manual Part Number61978-90030
EditionFirst Edition, November 2006

Frequently asked questions

How do I set up a method to use the multimode source?

In MassHunter software, change the Context to Acquisition, set Ion source to Multimode, choose an ionization mode (ESI, APCI, or Mixed), set source conditions, and save the method.

What safety precautions should I follow when using the multimode source?

Never bypass the LC diverter valve; connecting directly to the nebulizer may impair safety protections and cause fire.

What ionization modes are supported by the multimode source?

The multimode source supports ESI, APCI, and Mixed (simultaneous ESI and APCI) modes.

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