Agilent 1100 Series Purification System Mass-Based Fraction Collection Application Note

Mass-based fraction collection of compound libraries using the Agilent 1100 Series purification system

Brand: Agilent
Document type: Application Note
Language: English
Pages: 4
File format: PDF
File size: 459 KB
Published: 02 July, 2012
Updated: 01 October, 2023
Model: 1100 Series
MD5 checksum: A2033184DFA7E00CF681634D150247C0
PDF: Agilent 1100 Series Purification System Mass-Based Fraction Collection Application Note PDF

About this manual

The document describes a method for efficiently purifying compound libraries generated by combinatorial chemistry. It utilizes the Agilent 1100 Series purification system, which combines an analytical scale LC/MSD setup with fraction collection capabilities to isolate target compounds based on specific mass-to-charge ratios.

What's inside

Introduction
Equipment
Sample Preparation
Mass-based Fraction Collection
Results and Discussion
Chromatographic Conditions
MS Conditions
Conclusion

Frequently asked questions

What software controls the Agilent 1100 Series purification system?

The system is controlled using Agilent ChemStation and Purification/HighThruput software.

What is the main flow rate used in the described chromatographic method?

The main flow rate is set to 1 mL/min.

Download PDF (459 KB)