Agilent Proton Decoupled Deuterium NMR using Scout Scan for Lock Application Note

About this manual

This document explains the Scout Scan technique, pioneered by Agilent, which uses a single transient, low tipangle pulse to determine solvent signal frequencies. These frequencies are used to compensate for magnet drift or shift changes, particularly useful in applications like LC-NMR or analysis of biofluids where deuterium locks are inconvenient. The technique allows for the use of completely protonated solvents.

What's inside

• Proton Decoupled Deuterium NMR
• Scout Scan for Lock
• Magnetic Field Drift Compensation
• LC-NMR Applications
• Biofluid Analysis
• Deuterium Lock Alternatives
• Patented Scout Scan Technique

Frequently asked questions

How often must a Scout Scan be performed to compensate for magnetic field drift during deuterium NMR acquisitions?

A Scout Scan needs to be done every 512 transients or so to provide adequate compensation for magnetic field drift.

What specific type of NMR spectra can be observed using the Scout Scan technique with proton decoupling?

The technique allows for the unlocked direct observation of deuterium NMR spectra with proton decoupling.