Industrial

Absolute quantitation with the Agilent 2100 Bioanalyzer and the Protein 200 LabChip® kit. The Protein 200 LabChip® kit allows sizing and quantitation of proteins ranging in size from 14 to 200 kD. Relative quantitation is performed in comparison to the upper marker, used as internal standard in each sample. However, the accuracy of the relative quantitation is affected by the staining efficiency of the protein dye. Absolute quantitation is enabled with the Agilent 2100 bioanalyzer software (revision A.02.01) using the Protein 200 assay in combination with protein standards of known concentrations. Absolute quantitation improves quantitation accuracy by eliminating the differences in staining efficiency among proteins. This Application Note describes how to perform absolute quantitation with the Protein 200 assay and demonstrates the obtained improvement in accuracy.

The document describes the detection of the major metabolite of cocaine in the hair of 2000-year-old Chilean mummies. This is particularly important in relation to Rohypnol® because victims of the drug may not immediately realize they have been violated. However, hair analysis is challenging due to the difficulty in digesting the matrix and the low concentrations of the metabolite. Therefore, the sensitivity must be in the picogram per milligram range. The metabolism of flunitrazepam produces the 7-aminoflunitrazepam metabolite through the reduction of the nitro-group. Flunitrazepam is a benzodiazepine marketed by Hoffman-La Roche under the brand name of Rohypnol®. It is not legally used in the United States, but its abuse has been increasing in the southern and southwestern regions. The relatively low street price and high potency of Rohypnol® are of particular concern.

This Application Note describes results in protein impurity testing and simultaneous molecular mass characterization with the Agilent 1100 Series GPC-SEC analysis system.

The sequencing of oligosaccharides in glycosylated natural products was successfully investigated using liquid chromatography-mass spectrometry with electrospray ion source in negative ion mode.

DS2101SY is a double-sided cooled Zener diode produced by Dynex Semi. It has a maximum reverse voltage of 1500V, a rated average forward current of 7810A, and a rated peak forward current of 79000A.

This application note introduces the use of the VTO and rT on-state characteristic model and a more accurate alternative.

DS2070W 3.3V single-piece 16Mb nonvolatile SRAM

The DS2129 is a triple-output voltage regulator for 27-line, low-voltage-differential (LVD) SCSI termination for SPI-2 and SPI-3 applications using LVD termination networks. The device provides reference voltages and bias currents for LVD-termination resistor pi (π) networks. With a pi network (475Ω, 121Ω, 475Ω), the DS2129 meets the common-mode bias, differential bias, and termination-impedance requirements of SPI-2 (Ultra2) and SPI-3 (Ultra3). The device also provides a 1.3V output for DIFFSENSE signaling, and includes pro- tection features such as thermal shutdown and active current limiting.

DS1963S is a financial iButton with SHA-1 functionality and a 4k-bit read/write data area. It has a 4096-bit non-volatile (NV) memory, divided into 16 pages of 256 bits each. It also features independent 64-bit keys and 32-bit read-only, non-rolling page write counters. The device also includes a 512-bit SHA-1 engine that can calculate a 160-bit message authentication code (MAC) and can be used as a co-processor for roaming iButtons or hosts.

The DS2045W is a 1Mb reflowable nonvolatile (NV) SRAM, consisting of a static RAM (SRAM), an NV controller, and an internal rechargeable manganese lithium (ML) battery. It is housed in a surface-mount module with a 256-ball BGA footprint. When VCC is applied to the module, it recharges the ML battery, powers the SRAM from the external power source, and allows the contents of the SRAM to be modified. When VCC is powered down or out of tolerance, the controller write-protects the SRAM’s contents and powers the SRAM from the battery. The DS2045W also contains a power-supply monitor output, RST, which can be used as a CPU supervisor for a microprocessor.

DS2045Y/AB Single-Piece 1Mb Nonvolatile SRAM

The DS2045L is a 1Mb reflowable nonvolatile (NV) SRAM, which consists of a static RAM (SRAM), an NV controller, and an internal rechargeable manganese lithium (ML) battery. These components are encased in a surface-mount module with a 256-ball BGA footprint. Whenever VCC is applied to the module, it recharges the ML battery, powers the SRAM from the external power source, and allows the contents of the SRAM to be modified. When VCC is powered down or out-of-tolerance, the controller write-protects the SRAM’s contents and powers the SRAM from the battery. The DS2045L also contains a power-supply monitor output, RST, which can be used as a CPU supervisor for a microprocessor.

The DS2030 is a 256kb reflowable nonvolatile (NV) SRAM, which consists of a static RAM (SRAM), an NV controller, and an internal rechargeable manganese lithium (ML) battery. These components are encased in a surface-mount module with a 256-ball BGA footprint. Whenever VCC is applied to the module, it recharges the ML battery, powers the SRAM from the external power source, and allows the contents of the SRAM to be modified. When VCC is powered down or out of tolerance, the controller write-protects the SRAM's contents and powers the SRAM from the battery. Two versions of the DS2030 are available, which provide either a 5% or 10% power-monitoring trip point. The DS2030 also contains a power-supply monitor output, RST, which can be used as a CPU supervisor for a microprocessor.