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This document discusses how to control technical variability in microarray experiments, how to standardize microarray data, and how to validate microarray data. It also introduces a comprehensive portfolio of microarray tools designed to control errors, standardize platforms, and simplify experimentation.

Agilent genomics product portfolio, let you explore the possibilities of genome

This document introduces the benefits of Agilent OpenLAB Partner Program for developers, including product training, technical support and marketing promotion.

Agilent GPC/SEC Solutions Provide Innovative Polymer Analysis

Use RapidFire technology to accelerate discovery throughput assay development, HTS, and ADME

Agilent 7820A GC and 5975E GC/MSD are high-value products in the Agilent GC and GC/MS instrument portfolio, ideal for routine GC analyses that require high reliability, high reproducibility, and minimal maintenance.

Agilent J&W DB-624UI and DB-Select 624UI <467> GC columns lower detection limits and quantify trace-level organic volatile impurities

ProSep is a novel gas chromatography separation method that eliminates solvent before the column by installing a pre-separation column at the injection point, thereby avoiding the interference of solvent and improving the sensitivity. It shows excellent performance in a wide range of applications.

This application note describes large-volume injection (LVI) with a cool on-column (COC) inlet and solvent vapor exit (SVE) kit and is illustrated with examples of straight-chain hydrocarbons, polycyclic aromatic hydrocarbons (PAHs), and semivolatiles.

A multiple headspace extraction capillary gas chromatographic (MHE-CGC) method for the quantitative, accurate, and rapid determination of volatile components in solids such as polymers, resins, and activated carbon has been developed. A five-step MHE determination was performed using the Agilent 7694 headspace sampler and a 5890 Series II GC with EPC. A Microsoft® Excel spreadsheet was used to quickly perform the required calculations. Details of the procedure and implications affecting the analysis of polymeric materials are discussed.

This document describes the application of Agilent 7683 automatic liquid sampler (ALS). ALS can be used to perform thermostatted headspace analysis and ambient headspace analysis. The benefits of using ALS include increased sample throughput, reduced equipment cost, and simplified operation.

Agilent Technologies has developed a chemical sensor, the Agilent 4440A, which can rapidly distinguish among similar products with volatile constituents. The instrument consists of a modified Agilent headspace autosampler coupled directly to a modified Agilent mass selective detector. Unlike headspace gas chromatography with mass selective detection (HS/GC/MS), this system has no GC, and there is virtually no separation of the volatile constituents. Instead, the headspace volatiles are transferred directly to the mass selective sensor, which typically gives rise to a single broad peak composed of all the volatile constituents in the sample. Because the mass spectra of all these compounds are also overlaid, multivariate analysis and pattern recognition software are used to classify the samples. The advantages of this system over conventional HS/GC or HS/GC/MS are its speed and ease of use. Samples can be analyzed every 2 to 6 minutes, depending upon the amount of headspace equilibration time required, and operator training takes less than an hour. This application note discusses how the 4440A chemical sensor has been used to discriminate among various products. Most interestingly, this application note also shows how to use the information from the 4440A chemical sensor to identify unknowns.

This application note describes how to use Agilent Technologies’ retention time locking (RTL) software to match the retention time of an automated headspace GC system with that of a standard sample. RTL software allows the retention times of any Agilent 6890 Series or Agilent 6850 gas chromatograph (GC) system to be matched precisely to those of any other, as long as the systems are equipped with electronic pneumatics control. The results from different systems are virtually identical, independent of inlet, detector, operator, or location.

This article discusses how to increase the maximum achievable oven program rate by reducing the GC oven volume to shorten the GC analysis time. Comparisons were made between the Agilent 6890 Plus GC with Oven Insert and the Agilent 6850 Series GC, showing a dramatic increase in oven program rate with the use of the 6890 GC oven insert.

Retention time locking (RTL) is used to lock retention times when transferring methods from chromatographic instrument to chromatographic instrument, column to column, and detector to detector. This article discusses the application of RTL in forensic drug testing, specifically for the analysis of cocaine and its derivatives. The study shows that by locking the retention times of a derivatized cocaine standard, it is possible to achieve consistent retention times across different instruments and during routine maintenance procedures.