Thermo Scientific TSQ Triple Quadrupole Mass Spectrometer Application Manual

About this manual

The TSQ series is Thermo Scientific’s triple quadrupole mass spectrometer line, featuring a conjugate hyperbolic quadrupole analyzer that delivers high‑resolution SRM detection for quantitative and qualitative analysis. It is widely applied in food safety, environmental, agricultural, and regulatory testing.

The manual provides detailed LC‑MS/MS methods, sample‑preparation workflows (including QuEChERS), and software guidance (TraceFinder™ and Xcalibur) for analyzing residues of pesticides, veterinary drugs, and biological toxins in various food matrices. It also includes regulatory references and a quick‑screening method package for high‑throughput screening. This manual is written in Chinese.

What's inside

• Introduction to TSQ Triple Quadrupole MS
• Food Safety Applications
• Pesticide Residue Analysis
• Veterinary Drug Residue Analysis
• Biotoxin Analysis
• Sample Preparation and QuEChERS
• Instrument Settings and SRM Mode
• Data Processing Software (TraceFinder, Xcalibur)
• Regulatory Guidelines and References
• Appendix

Specifications

Frequently asked questions

Which software is recommended for data processing with the TSQ system?

The manual recommends using TraceFinder™ and Xcalibur for data acquisition, processing, and reporting.

What sample‑preparation method is suggested for multi‑residue pesticide analysis?

The guide suggests using the QuEChERS method for efficient extraction and cleanup of pesticide residues.

Which detection mode provides the highest sensitivity on the TSQ instrument?

SRM or H‑SRM acquisition modes are used to achieve high sensitivity and selectivity.