The 5975 inert MSD – Benefits of Enhancements in Chemical Ionization Operation Technical Note This Technical Note describes the complete integration of chemical ionization (CI) on the 5975 inert MSD (mass selective detector), which now makes all the power of CI mass spectrometry (MS) conveniently available. CI has been fully automated by providing auto-tuning with electronic control of the reagent gases. All modes of MS operation in a single sequence, completely free of operator intervention, are now possible. Analytes can be sensitively determined in samples by implementing alternating positive- or negative-CI (PCI or NCI) modes. On the 5975 inert MSD, CI is as easy as EI (electron impact ionization).
The document details how the Agilent 5975 inert MSD integrates Chemical Ionization (CI) with Electron Impact (EI) ionization. Key enhancements include fully automated auto-tuning for both EI and CI modes, as well as complete electronic control of reagent gases (methane and ammonia). This integration allows analysts to switch between positive-ion chemical ionization (PCI) and negative-ion chemical ionization (NCI) within a single sequence without manual intervention.
| Reagent Gas Options | Methane and Ammonia |
|---|---|
| Maximum MFC Flow | 5 mL/min |
The instrument supports Methane and Ammonia as reagent gases.
Yes, the instrument allows alternating between positive- or negative-Cl (PCI or NCI) modes within a single sequence.