Agilent 6890/5973 GC/MSD BFB Tuning Application Note

About this manual

This document outlines tuning criteria for USEPA methods 524.2, 8260B, and the Contract Laboratory Program Statement of Work (CLP-SOW) regarding 4-bromofluorobenzene (BFB) analysis. It details how the Agilent 6890/5973 gas chromatograph/mass selective detector system can be adjusted to meet these specific ion abundance requirements.

The text presents three distinct approaches to achieve a successful tune: using the standard automated procedure, modifying the autotune targets for improved sensitivity, and utilizing a specific 'Modified Autotune' procedure developed by the authors. It includes tables of criteria and screenshots of the EnviroQuant ChemStation software interface used for evaluation.

What's inside

• Introduction
• Tuning Criteria
• Automated BFB Tuning
• Target Tuning
• Modified Autotune
• Tune Evaluation

Frequently asked questions

What concentration of BFB standard was used for the manual injection shown in Figure 1?

The procedure involved a 1-uL injection of a methanol solution containing 50 ng/uL of BFB.

What is the maximum allowed relative abundance for m/z 174 under CLP-SOW requirements?

The CLP-SOW method allows the m/z 174 response to be up to 120% of the m/z 95 base peak.

Where is the BFB tune evaluation report archived by default?

The most recent report is saved in the datafile.d directory inside a file named tuneeval.txt.