This document introduces the application of Agilent PLgel MIXED-E gel permeation chromatography technology in the analysis of phenolic resins. Gel permeation chromatography of phenolic resins can be easily performed using Agilent PLgel 3µm MIXED-E columns, which are suitable for both low molecular weight samples and high molecular weight samples. In addition, for more difficult polar resins, Agilent PolarGel columns are preferred for analysis.
This document details a method for analyzing phenol-formaldehyde reactions, specifically novolacs and resols, using Gel Permeation Chromatography (GPC). The procedure utilizes ultra high efficiency Agilent PLgel 3 µm MIXED-E columns to achieve excellent oligomeric detail for samples up to 30,000 MW.
The note provides specific chromatographic conditions, including a two-column setup of 2 x Agilent PLgel 3 µm MIXED-E (7.5 mm), THF as the eluent, and a flow rate of 1.0 mL/min detected by UV. It also notes that for difficult polar resins, PolarGel columns are preferred.
| Column Type | 2 x Agilent PLgel 3 µm MIXED-E, 300 = 7.5 mm |
|---|---|
| Eluent | THF |
| Flow rate | 1.0 mL/min |
| Detector | UV |
| System | Agilent PL-GPC 50 |
Agilent PLgel 3 µm MIXED-E columns are ideal for these samples.
The columns can analyze polymers up to 30,000 MW.
Agilent PolarGel columns are preferred for use with polar solvents.