This document is the user guide for the 4000 MS mass spectrometer by Varian, Inc. It provides an overview of the internal configuration, scan functions, sample introduction, ionization, fragmentation, ion storage, ion preparation, ion analysis, and more. It also mentions that Varian, Inc. was acquired by Agilent Technologies in 2010.
The document serves as a user guide for the Agilent Technologies 4000 MS system operating in Internal Ionization mode. It details the capabilities of collecting Electron Ionization (EI) or Positive Chemical Ionization (PCI) data during different time segments of a single chromatographic acquisition, noting that Negative Chemical Ionization is not supported in this configuration. The guide explains the internal ion trap analyzer process, including sample introduction, ion formation, storage, and analysis.
| Supported Ionization Modes | Electron ionization or positive chemical ionization (EI or PCI) |
|---|---|
| Unsupported Mode | Negative Chemical Ionization |
| Analyzer Type | Ion trap analyzer |
No, it is not possible to collect Negative Chemical (NCI) data in Internal configuration.
The system can collect Electron Ionization (EI) or Positive Chemical Ionization (PCI) data.
Yes, unlike the External Ionization configuration, it is possible to collect EI or PCI data during different time segments of a single chromatographic acquisition.