Industrial

This document describes an LC system for online 2D LC/MS, which uses an effective continuous salt solution gradient in the first dimension. The results will be compared to previously obtained results.

This Application Note describes the configuration and set up of a purification system for the isolation of radiolabeled drug metabolites from biological samples applied by an injection pump system. Various fraction collection options, for example, time-based fraction collection monitored by a radiochemical detector or peak-based fraction collection on the radiochemical detector signal are described.

PT6300 Series is a line of High-Performance 3 Amp, 12-Pin SIP (Single In-line Package) Integrated Switching Regulators (ISRs) designed to meet the on-board power conversion needs of battery powered or other equipment requiring high efficiency and small size. It offers a unique combination of features combining 90% typical effi- ciency with open-collector on/off control and adjustable output voltage.

The present invention discloses a new type of liquid chromatography column, which has a short column length and small particle size, and can achieve efficient high-throughput analysis.

This method uses the Agilent Total RNA Isolation Mini Kit to isolate high-purity RNA from yeast cells. The method has the advantage of removing cellular contaminants such as proteins, carbohydrates, and genomic DNA, resulting in a purer RNA product. The method uses a carefully prepared yeast spheroplast followed by complete homogenization of the sample to remove high levels of cell wall components and other proteins, thus achieving high efficiency in the separation of yeast RNA. Compared with other commercial methods, the Agilent method yields comparable yeast total RNA yield and contains significantly less genomic DNA than RNA isolated with a competitor's silica-based kit. Agilent 2100 Bioanalyzer analysis showed that the isolated RNA had high quality and integrity.

This Application Note demonstrates the mass-based purification of low gram amounts of compounds using the Agilent 1100 Series purification platform. Starting the experiments on 21.2-m i.d. columns two application examples were scaled up to a 50-mm i.d. column operated at 100 mL/min. Fractions with purities of 85 and 95 % were obtained by mass-based fraction collection even though the column overload did not allow the UV-trace to show separated peaks.

The PT6310 series is a high-performance 2 Amp, 12-pin SIP (Single In-line Package) Integrated Switching Regulator (ISR) designed to meet the on-board power conversion needs of battery powered or other equipment requiring high efficiency and small size. This high-performance ISR offers a unique combination of features combining 87% typical efficiency with open-collector on/off control and adjustable output voltage.

The PT6310 series is a high-performance 2A, 12-pin SIP integrated switching regulator designed to meet the on-board power conversion needs of battery powered or other equipment requiring high efficiency and small size.

PT6305 series is a 3-amp high-performance adjustable ISR with a static voltage tolerance of 3.2-3.4V, a switching frequency of 500-800KHz, a working voltage range of 4.5-9V, an output current range of 0.3-3.0A, and an efficiency of 80-85%

This application note describes the possibilities of networking computers in an analytical laboratory using Agilent instrumentation and data systems. The benefits of networking are introduced, as well as how to use the IEEE 802.11b standard to achieve wireless network connectivity.

This document describes the different levels of instrument control with chromatography data systems and their implications for compliance. It provides a checklist for evaluating the capability of instrument control and data handling software.

This document provides a general method for using finite element analysis in engineering modeling tools and system simulation tools. The goal of this method is to provide a structured method for creating finite element models and integrating them into larger engineering modeling and system simulation systems.

This application note describes how the Agilent 2100 bioanalyzer can be used for the detection of a point mutation in the human prothrombin gene. The prothrombin protein plays a key role in blood clotting. A single nucleotide polymorphism (SNP), i.e. a point mutation in the prothrombin gene results in a common hereditary predisposition to venous thrombosis. We present a convenient and reliable mutation detection method by a PCR-based assay including a specific restriction digest (PCR-RFLP). Due to its high sensitivity and resolution, the applied microfluidic assay proves to be extremely suitable for detec- tion of the obtained PCR products and restriction fragments. The developed method is suitable for the workflow at Laborigo molecular diagnostic laboratory.