The 5975 inert MSD – Benefits of Enhancements in Chemical Ionization Operation Technical Note This Technical Note describes the complete integration of chemical ionization (CI) on the 5975 inert MSD (mass selective detector), which now makes all the power of CI mass spectrometry (MS) conveniently available. CI has been fully automated by providing auto-tuning with electronic control of the reagent gases. All modes of MS operation in a single sequence, completely free of operator intervention, are now possible. Analytes can be sensitively determined in samples by implementing alternating positive- or negative-CI (PCI or NCI) modes. On the 5975 inert MSD, CI is as easy as EI (electron impact ionization).