Agilent Manuals

This Application Note describes a method to analyze traces of potential genotoxic impurities (PGIs) in pharmaceuticals using the Agilent 1290 Infinity LC system and a 60 mm Agilent Max-Light Cartridge Cell, which offers maximum sensitivity.

This Application Note demonstrates the high resolution separation of a pharmaceuti- cal test mixture, a pesticide standard and a cosmetic sample on a 1 m column (4 × 25 cm) using the Agilent 1260 Infinity Analytical SFC system.

This application note describes the conditions for the determination of trace sulfur compounds using the PFPD.

This application note describes the analysis of furfurals in wood sugar solutions obtained by low environmental impact hydrothermal treatment and mechanochemical treatment followed by enzyme-based glycosylation using the Agilent 1260 Infinity LC system.

This paper describes a method for the separation of the 15 priority PAHs of the European Union’s (EU’s) Scientific Committee on Food (SCF) with benzo[c]fluorene, deemed relevant by the Joint FAO/WHO Experts Committee on Food Additives (JECFA).

The Xcalibur E is a fully automated X-ray crystallography instrument for crystal to structure applications. It features a user-friendly interface and allows for fast and accurate chemical structure determination. Unlike other bench-top instruments that are limited to studying routine large crystals, the Xcalibur E is capable of handling crystals of various sizes and qualities. With its compact design and upgrade options for dual wavelength and CCD, it provides high-quality crystal structures with minimal user intervention in a short amount of time.

The PX Scanner is a revolutionary product from Agilent Technologies designed specifically for the in-situ identification and analysis of protein crystals within multi-well crystallisation plates. This application note presents a collection of experimental results obtained using the PX Scanner.

Highly Sensitive UV Analysis with the Agilent 1290 Infinity LC System for Fast and Reliable Cleaning Validation – Part 3 Determination of residual active pharmaceutical impurities from a previous production batch using a DAD with standard or high sensitivity flow cell

This application demonstrates the use of electron impact GC–MS for trace-level PBDE analysis. The method uses Agilent J&W DB-5ms Ultra Inert GC column. This column has been thoroughly tested for column inertness and provides the analyst with high confidence in the accuracy of the results.

This document describes the results of trace-level PAH analyses using Agilent J&W DB-5ms Ultra Inert 30 m × 0.25 mm, 0.25 µm capillary GC column on a 16-component PAH standard mixture.

This paper introduces a new type of X-ray source for the characterization of the crystal structures of derivatized resorcarenes, which has both Mo and Cu X-ray radiation sources, and experimentally verifies its effectiveness in the characterization of the crystal structures of derivatized resorcarenes.

Gemini A is a dual wavelength diffractometer suitable for modern small molecule crystallography laboratories. Designed and brought to you by the world’s leading manufacturers of dual wavelength systems, the Gemini A is a compact and easy-to-use instrument combining the versatility and benefits of co-mounted both molybdenum and copper Enhance X-ray sources on a single 4-circle kappa goniometer.

This document describes the use of Xcalibur PX Ultra to collect highly redundant data from cubic insulin at York Structural Biology Laboratory, demonstrating protein structure phasing using the sulfur anomalous signal. The document provides details on the data collection, indexing, integration, and refinement processes.

This Application Note introduces the “Follow sudden changes of sample orientation” tool in CrysAlisPro’s data reduction software. This tool can track crystal movement and correct for the data affected by it.

This article describes the application of CrysAlisPro software tools in handling data sets of non-Merohedral crystals. By using the software tools of CrysAlisPro, it is relatively easy to obtain high-quality structures.