This document introduces the features and advantages of Agilent LC/MSD TOF mass spectrometer, including high mass resolution and high mass accuracy, as well as atmospheric pressure ionization sources. It can confirm the empirical formulas of small molecule organic compounds and identify unknown compounds.
This document explains the theory and concepts behind mass resolution and mass accuracy and how they affect the ability to unambiguously confirm empirical formulas of small molecule organic compounds or identify unknowns. It highlights that both very good mass resolution and mass accuracy are required to positively distinguish between compounds with the same nominal mass.
The text details the design elements of the Agilent LC/MSD TOF that enhance its resolving power and mass accuracy. These include a beam shaper, one-dimensional harp grids, and an analog-to-digital acquisition system with an automated calibrant delivery system for continuous mass correction.
| Resolving Power at 100 u | 2,000 |
|---|---|
| Resolving Power at 1000 u | 20,000 |
| Mass Accuracy at 120 u | approximately 4 ppm |
It uses an analog-to-digital acquisition system combined with an automated calibrant delivery system and a second nebulizer to allow continuous introduction of a reference mass compound for mass correction.
It is designed for empirical formula confirmation of small molecule organic compounds.
The instrument has a mass accuracy of approximately 4 ppm at 120 u.
It uses an analog-to-digital acquisition system combined with an automated calibrant delivery system and a second nebulizer.