The Agilent 1260 Infinity Bio-inert Quaternary LC system has the same performance specifications as the standard Agilent 1260 Infinity Quaternary LC system based on the proven technology of the Agilent 1200 Infinity Series. This Technical Overview proves that method transfer from an Agilent 1260 Infinity Series Quaternary LC system to an Agilent 1260 Infinity Bio-inert Quaternary LC system will typically result in chromatograms with no significant differences including compatibility with standard methods with a maximum pressure of 600 bar. In addition, it is especially well suited for bio-analytical applications, such as, protein analysis using ion exchange chromatography (IEX) or size exclusion/gel filtration (SEC).
This document serves as a technical overview for the Agilent 1260 Infinity Bio-inert Quaternary LC system, designed specifically for bio-chromatography applications. It demonstrates that the system maintains the same performance specifications as the standard 1260 Infinity Quaternary LC system, supporting a maximum pressure of 600 bar and compatibility with standard methods.
| Maximum pressure | 600 bar |
|---|---|
| Maximum temperature | 80 °C |
| Flow rate range | up to 5 mL/min |
| Retention time precision (gradient) | < 0.08 % RSD |
| Retention time precision (fast gradient) | < 0.11% RSD |
| Retention time precision (isocratic) | < 0.1% RSD |
| Ripple on 10% step | 0.07% |
| Ripple on 50% step | 0.06% |
| Ripple on 90% step | 0.07% |
| System delay volume | 1,000 pL |
| Area precision (1 pL injection) | <0.33 % |
| Area precision (0.5 pL injection) | <0.75% |
Yes, it is compatible with standard methods with a maximum pressure of 600 bar.
The system supports a maximum pressure of 600 bar.
The system has a maximum temperature of 80 °C, or 100 °C with an Agilent 1290 Infinity Thermostatted Column Compartment.
Yes, it is especially well suited for bio-analytical applications, such as protein analysis using ion exchange chromatography or size exclusion/gel filtration.