Agilent low bleed GC/MS columns are specifically designed to overcome the challenges of low level trace analysis. These columns have low bleed and high temperature performance, providing more accurate results without compromising analysis time.
This document introduces a new generation of thermally resistant, low bleed capillary columns from Agilent Technologies (J&W Scientific). These columns are specifically engineered to meet the demands of modern benchtop mass spectrometers and ion traps by reducing background noise and improving spectral purity at elevated temperatures.
The text details four specific column options: DB-5ms, DB-XLB, DB-35ms, and DB-17ms. It explains that these columns utilize unique polymer chemistry and proprietary surface deactivation technology to achieve lower bleed levels while maintaining selectivity virtually identical to their conventional counterparts. The document highlights benefits such as extended upper temperature limits (up to 360°C), improved inertness for acidic and basic samples, and shorter analysis times.
| Upper temperature limit (isothermal) | 325 C for DB-5ms, 340/360 C for DB-XLB and DB-35ms |
|---|---|
| Upper temperature limit (program) | 350 C for DB-5ms, 360 C for DB-XLB and DB-35ms |
| Selectivity type | Standard 5% phenyl siloxane phase |
| Selectivity type | 35% phenyl siloxane |
They utilize special surface deactivation and siloxane chemistries that enhance chromatographic performance while adhering to tight quality control specifications.
No, in most cases all benefits of low bleed columns can be realized without any noticeable shift in analyte retention.
DB-XLB has no conventional counterpart and offers excellent inertness, higher temperature limits, and unique selectivity for trace analytical work.