This application note describes how to use Agilent Technologies’ retention time locking (RTL) software to match the retention time of an automated headspace GC system with that of a standard sample. RTL software allows the retention times of any Agilent 6890 Series or Agilent 6850 gas chromatograph (GC) system to be matched precisely to those of any other, as long as the systems are equipped with electronic pneumatics control. The results from different systems are virtually identical, independent of inlet, detector, operator, or location.
Agilent Technologies' retention time locking (RTL) software allows chromatographers to match retention times precisely between different 6890 Series or 6850 gas chromatograph (GC) systems equipped with electronic pneumatics control. This ensures that results from different systems are virtually identical, independent of inlet, detector, operator, or location.
The document details the RTL calibration process involving five runs at varying inlet pressures to generate a calibration file within the ChemStation software. It further describes an experimental verification using a 6890 Plus GC with a 7694A headspace autosampler and a USP 467 standard sample to demonstrate retention time precision after column trimming.
The software works with any Agilent 6890 Series or 6850 gas chromatograph (GC) system equipped with electronic pneumatics control.
The USP 467 protocol suggests that carrier gas linear velocity should be about 35 cm/s.
Agilent's RTL software (G2080AA) integrates into the Agilent ChemStation version A.05.02 or later.