A single, rapid GC method for aromatic solvent purity analysis is described. The application of a high-efficiency 0.18-mm-id GC column results in faster analyses compared to conventional 0.25-mm- or 0.32-mm-id columns without losing mea- surement performance.
This document details a method for the fast analysis of aromatic solvents using high-efficiency 0.18 mm internal diameter (ID) capillary columns. It addresses the need for increased sample throughput in QA/QC laboratories by reducing analysis time compared to conventional 0.25 mm or 0.32 mm ID columns without sacrificing measurement performance.
The note presents experimental results obtained using Agilent 6890N and 7890 gas chromatographs equipped with an Agilent 7683 Automatic Liquid Sampler. It compares three methods: a conventional method using a 60 m x 0.32 mm column, a method using a high-efficiency 20 m x 0.18 mm column, and an optimized fast analysis method. The document provides specific experimental conditions, including carrier gas pressure, inlet temperature, oven temperature programs, and detector settings, demonstrating that the optimized method achieves baseline separation for critical compound pairs like dodecane and o-xylene.
| Column Type | HP-INNOWax |
|---|---|
| Column Dimensions (Method 2) | 20 m x 0.18 mm x 0.18 um |
| Carrier Gas | Helium |
| Inlet Temperature | 250 °C |
| Detector Type | FID |
| Detector Temperature | 250 °C |
They provide higher efficiency per unit of column length, allowing for shorter column lengths and faster analyses compared to conventional columns without losing measurement performance.
The analysis was performed using one Agilent 6890N Series gas chromatograph and two Agilent 7890 gas chromatographs.
Method 3 uses a shorter 20 m x 0.18 mm column with a higher initial oven temperature (70 °C) and a faster heating rate (45 °C/min) compared to the conventional 60 m x 0.32 mm column.