Agilent Manuals

This Application Brief describes the use of an Agilent 6410 Triple Quadrupole Mass Spectrometer (QQQ) to analyze perfluorooctanoic acid (PFOA). A simple isocratic elution is carried out on a Rapid Resolution High Throughput C18 column (particle size 1.8 µm) with only water and methanol solvents containing 10 mM ammonium acetate. Elution time for standard dilutions of PFOA is only 2.3 minutes. Good linearity over more than 4 orders of magnitude, from 9 fg/µL to 150 pg/µL, is demonstrated with excellent peak area reproducibility of 5.5 % RSD at the 9 fg/µL level. The average peak-to-peak signal-to-noise (S/N) ratio at this level is 7.2. Sensitivity of surface water extracts is expected to be similar.

The new Agilent 7500cx allows the user to achieve the full potential of ICP-MS for semiquantitative elemental screening of a wide range of sample types. Complex, unknown samples can be analyzed with better speed, accuracy, and data integrity than ever before, since all matrix interferences are removed in the Octopole Reaction System (ORS) using helium collision mode. Results are presented for three different certified reference materials.

The method is based on the use of a mixed 119Sn-enriched spike and uses GC-MS coupled with electron impact ionization to simultaneously determine monobutyl, dibutyl, and tributyltin in water, sediments, and biota.

Rapid Analysis of High-Matrix Environmental Samples Using the Agilent 7500cx ICP-MS Application

This abstract describes the application of the Agilent 6510 Quadrupole Time-of-Flight Mass Spectrometer (QTOF) for the analysis of pharmaceutical compounds in water.

Definitive Quality Control of Titania Coatings with the Agilent 7020 ZetaProbe

Explains how the Agilent 7020 ZetaProbe can be used to control the stability of a colloid

This Application Note describes the nature of the electrostatic potential near the surface of a particle, called the zeta potential. It explains how the zeta potential is determined by measuring the velocity of the particles in an electric field. It also explains how the charge on the particle surface affects properties of suspensions and emulsions.

This paper introduces a new method for environmental semivolatiles detection using a triple-axis detector (TAD) to achieve femtogram GC/MSD detection limits with improved sensitivity. The method uses liquid-solid extraction (LSE) with C18 disks or columns for sample extraction, 1 µL hot split-less injection for sample injection, and MS operating in full-scan mode. This method significantly improves the sensitivity to the femtogram level when measuring acids, bases, neutrals, and pesticides in drinking water and source water.

This study uses two types of discharge compounds (an insecticide and a pulp mill condensate) to illustrate the LC/Q-TOF sensitivity, linear range, quantitative, and qualitative analysis functionalities.

This document introduces the application of LC/Q-TOF in the analysis of dyes/pigments and other environmental compounds of interest, including sample preparation, LC/Q-TOF conditions optimization, mass spectrometry identification, and structure confirmation. This document is suitable for environmental research and analysis personnel.

This application demonstrates the trace-level analysis of polybrominated diphenyl ethers (PBDE) using electron impact single quadrupole scanning mass spectrometry. Agilent Technologies Inc. has implemented new testing procedures to evaluate the column inertness performance more effectively. The study focuses on the importance of PBDE analysis in understanding food supply and environmental quality worldwide.

This application note describes the application of EPA Method 1694 for screening and confirming the presence of 65 pharmaceuticals in water samples using the Agilent G6410A Triple Quadrupole mass spectrometer (QQQ).

This application note is targeted for ultra-high productivity of total petroleum hydro- carbons (TPH) analysis in environmental laboratories. Agilent's Low Thermal Mass (LTM) technology is employed here to perform ultra-fast gas chromatographic (GC) separations. The LTM technology uses a column module combining a fused silica cap- illary column with heating and temperature-sensing components wound around it, which can be heated and cooled very efficiently. In this application note, the speed of analysis for the hydrocarbon group eluting between C10 and C44 can be dramatically increased to about 13 times faster than a conventional method. In addition, the ultra- fast cooling function of an LTM module can reduce the total GC cycle time to 5.1 minutes. The simultaneous dual-tower injection from Agilent is used to further double productivity. The final result for TPH analysis productivity is 5.1 minutes per two samples.