Agilent MSD Productivity ChemStation Retention Time Locking Technical Overview

This document introduces the retention time locking (RTL) technology, which allows for the consistency of retention times on different instruments, simplifying method development and transfer.


Agilent MSD Productivity ChemStation Retention Time Locking Technical Overview - cover page
Brand
Agilent
Document type
User Manual
Language
English
Pages
6
File format
PDF
File size
132 KB
Published
05 July, 2012
Updated
29 September, 2023
MD5 checksum
76C02D52267B1335C2417236163BA547

About this manual

This document provides a technical overview of Retention Time Locking (RTL), a feature designed to match retention times on one Agilent Technologies GC/MSD or GC system to those on another like system. By adjusting the inlet pressure, RTL allows for the close matching of retention times using the same nominal column, which simplifies method transfer and compensates for chromatographic performance degradation.

What's inside

  • Introduction
  • What Is Retention Time Locking?
  • When Should I Lock My Methods?
  • How Does It Work?
  • Selecting the Standard Compound
  • Creating an RTL Method

Frequently asked questions

What is retention time locking (RTL)?

Retention time locking allows a close match of retention times on one Agilent Technologies GC/MSD or GC system to those on another like system with the same nominal column.

When should I lock my methods?

Locking or relocking your methods should be done whenever you make any changes to the chromatographic system or move methods from one system to another.

How many injections are needed for calibration?

Multiple (five) injections of the standard are used to calculate the retention times at predefined inlet pressures.

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