PL-HCO3 MP Resin is a quaternized macroporous polystyrene strong anion exchanger with a bicarbonate counter-ion. It provides the most convenient method of removing residual acids and counter-ions such as trifluoroacetate.
StratoSpheres PL-HCO3 MP Resin is a quaternized macroporous polystyrene strong anion exchanger with a bicarbonate counter-ion. It is designed to provide a rapid and cost-effective method for removing residual acids and counter-ions, such as trifluoroacetate, from pharmaceutical compounds without the need for specialized laboratory equipment or lengthy freeze-drying processes.
The resin is available in bulk format or pre-packed in SPE cartridges. It effectively removes a wide range of acids including trifluoroacetic acid, formic acid, and hydrochloric acid. The document details the simple protocol for preconditioning, applying the sample, and washing the sorbent to isolate the free base product, as well as recommended configurations for treating larger volumes of solution.
| Resin Type | Quaternized macroporous polystyrene strong anion exchanger |
|---|---|
| Counter-ion | Bicarbonate |
| Particle Size | Optimized for easy handling |
| Capacity (Bulk) | 1.8 mmol/g |
It can remove a wide range of acids including trifluoroacetic acid, formic acid, acetic acid, and hydrochloric acid.
No, it is economical and simple to use and requires no specialized laboratory equipment or instrumentation.
The only by-products from using StratoSpheres PL-HCO3 MP are water and carbon dioxide.