AmphiSpheres is a hydrophilic and hydrophobic polymer support with both polystyrene and polyethyleneglycol components, which can be used for solid-phase and solution-phase synthesis.
This document introduces the AmphiSpheres range of polymer supports designed for solid phase peptide synthesis. These materials combine hydrophobic polystyrene with hydrophilic polyethyleneglycol (PEG) chains to improve swelling characteristics across a wide range of solvents, facilitating better synthesis results.
| PEG Content (AmphiSpheres 20) | 20% w/w |
|---|---|
| Loading (AmphiSpheres 20) | 0.7 mmol/g |
| PEG Content (AmphiSpheres 40) | 40% w/w |
| Loading (AmphiSpheres 40) | 0.4 mmol/g |
The polyethyleneglycol chain imparts improved swell characteristics across a wide range of solvents, promoting better reactivity.
AmphiSpheres 20 has a 20% w/w PEG content and a loading of 0.7 mmol/g.
AmphiSpheres 40 has a 40% w/w PEG content and a loading of 0.4 mmol/g.
The available particle size for these resins is 75-150 um.