This document describes the application of the Agilent 400-MR instrument with ATB or ASW probes for the analysis of compounds containing 19F. The instrument can perform 1-D fluorine decoupled proton spectra, 1-D proton decoupled fluorine spectra, and 2-D proton-fluorine through-bond and through-space correlation experiments. The key benefits include simplified spectra, easy configuration and use, and robustness and reliability.
The Agilent 400-MR, when equipped with an Automated Triple Broadband (ATB) or AutoSwitchable (ASW) probe, is designed for the analysis of compounds containing fluorine-19 ('9F). The document highlights that these applications are included on a standard 400-MR system and require no special hardware or cabling.
| Spectrometer Model | 400-MR |
|---|---|
| Compatible Probes | ATB or ASW probe |
| Available Experiments | 1-D fluorine decoupled proton spectra, 1-D proton decoupled fluorine spectra, and 2-D protonfluorine through-bond and through-space correlation |
No, these applications are included on a standard 400-MR when equipped with a standard ATB or ASW probe.
Available experiments include 1-D fluorine decoupled proton spectra, 1-D proton decoupled fluorine spectra, and 2-D protonfluorine through-bond and through-space correlation.
Applications include drug discovery, organic synthesis confirmation, drug development, purity analyses, and metabolite identification and quantitation.