Agilent MassHunter Profiling Software for the Agilent 6210 TOF LC/MS Manual

The Agilent MassHunter Profiling software is specifically designed for expression profiling applications such as biomarker discovery. When used with the Agilent 6210 TOF LC/MS, the MassHunter Profiling software clearly identifies statistically meaningful differences between sample groups, allows selection of comparison criteria, and exports profile data for statistical analysis using Agilent's GeneSpring GX software, other database search programs, identification environments, or statistical analysis packages. MassHunter Profiling software also supports additional applications such as pharmaceutical impurity analysis, forensic analysis, environmental analysis, and pesticide analysis. Mass profiling is widely used to compare the expression of peptides, proteins, or metabolites for biomarker discovery in a variety of comparative studies (e.g., healthy versus diseased or drug-treated samples, monitoring disease states). Mass profiling can also be used for other applications, including the detection of pharmaceutical impurities and targeted compounds such as pesticides or drugs of abuse.


Agilent MassHunter Profiling Software for the Agilent 6210 TOF LC/MS Manual - cover page
Brand
Agilent
Category
Other Electronics
Document type
Product Leaflet
Language
English
Pages
4
File format
PDF
File size
264 KB
Published
03 July, 2012
Updated
29 September, 2023
MD5 checksum
822D9DC1282F03F67DE8D8DC781A5766

About this manual

The Agilent MassHunter Profiling software is specifically designed for expression profiling applications such as biomarker discovery. When used with the Agilent 6210 TOF LC/MS, the software identifies statistically meaningful differences between sample groups and exports profile data for statistical analysis using Agilent's GeneSpring GX software or other database search programs. It supports additional applications including pharmaceutical impurity analysis, forensic analysis, environmental analysis, and pesticide analysis.

The software utilizes a unique feature identification algorithm that locates components in complex peptide mixtures, effectively removing chemical background data and extracting low-level peptides. It provides visualization tools to identify statistically meaningful differences between sample groups, calculates ratios of abundances of differentially-expressed features, and allows flexible user selection of comparison criteria. Profiling data can be exported to Microsoft Excel, text files, or Agilent's GeneSpring GX software for further analysis.

What's inside

  • Expression profiling applications
  • Feature identification algorithm
  • Differential analysis
  • Data export options
  • Statistical tools

Frequently asked questions

What specific instrument is the MassHunter Profiling software designed for?

The software is specifically designed for use with the Agilent 6210 TOF LC/MS.

What types of applications does the software support besides biomarker discovery?

It supports pharmaceutical impurity analysis, forensic analysis, environmental analysis, and pesticide analysis.

What file formats can profiling data be exported to?

Data can be exported to a Microsoft Excel file, a text file, or Agilent's GeneSpring GX software.

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