Agilent PLAP-S/PL-SAX/PL-SCX Biomolecule Purification Media Leaflet

This document introduces Agilent's high-quality, high-performance rigid polymer purification columns and media for the purification of peptides, oligonucleotides, and proteins. These media are manufactured by controlled polymerization and modification of polystyrene/divinylbenzene (PS/DVB), providing optimized pore structure and surface chemistry for reproducibility. The key features include product free of contamination, increased sample loading capacity, and batch-to-batch reproducibility.


Agilent PLAP-S/PL-SAX/PL-SCX Biomolecule Purification Media Leaflet - cover page
Brand
Agilent
Category
Other
Document type
Product Leaflet
Language
English
Pages
12
File format
PDF
File size
4.4 MB
Published
03 July, 2012
Updated
28 September, 2023
MD5 checksum
2DB6A8716174D36BDD4BC0376AF37919

About this manual

This document introduces Agilent's high-performance polymeric particles for chromatographic applications, specifically PLAP-S (reversed-phase), PL-SAX (strong anion exchange), and PL-SCX (strong cation exchange). Manufactured using controlled polymerization of polystyrene/divinylbenzene (PS/DVB), these media are designed for the purification of biomolecules ranging from small peptides to large proteins and DNA fragments. The acquisition of Varian and Polymer Laboratories has positioned Agilent as a leading manufacturer in this specialty field.

What's inside

  • Highest quality performance
  • Rigid polymerics for chromatography
  • Key benefits of Agilent media
  • Parallel performance comparison
  • Solvent compatibility
  • Chemical and pH stability
  • Cleaning in place (CIP)
  • Physical and thermal stability
  • Optimized column lifetime
  • Optimized pore structure

Specifications

Media TypeRigid polymerics for high-quality prep-to-process chromatography
Material CompositionPolystyrene/divinylbenzene (PS/DVB)
PLAP-S ApplicationReversed-phase chromatography
PL-SAX ApplicationStrong anion exchanger
PL-SCX ApplicationStrong cation exchanger
Maximum Operating Pressure6000 psi
Maximum Operating Temperature60 °C
Manufacturing CapacityExcess of 4 metric tons

Frequently asked questions

What is the maximum operating pressure for Agilent polymeric media?

The particles are physically robust and stable up to 6000 psi.

Can Agilent PLAP-S media be used at elevated temperatures?

Yes, the media is thermally stable for separations requiring elevated temperatures, such as 60 °C.

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