Agilent SureSelect Target Enrichment System Product Note

About this manual

The Agilent SureSelect Target Enrichment System addresses limitations in next-generation sequencing by enabling specific targeting of genomic regions. Developed in collaboration with the Broad Institute, this system utilizes an efficient hybrid selection technique that significantly improves workflow efficiency, allowing for a larger number of samples per study while minimizing total sample costs.

What's inside

• Introduction
• Custom Kit Design
• RNA-Driven DNA Capture
• Enrichment Design Algorithms
• Read Distribution and Sequence Coverage

Frequently asked questions

What is the minimum sample input requirement for the SureSelect Target Enrichment System?

The system works with sample input requirements at or below 3 picograms of genomic DNA.

How long must size-selected libraries be incubated with SureSelect baits?

Size-selected libraries are incubated with SureSelect baits for 24 hours.

What is the typical range of fold enrichment achieved by the SureSelect Target Enrichment System?

The system demonstrates enrichments of 300 to 7400 fold.