Agilent Manuals (Industrial)

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This document describes an improved method for the simultaneous measurement of sirolimus and tacrolimus concentrations in blood, in which the drugs are first isolated from whole-blood specimens by solid phase extraction and then analyzed by liquid chromatography and electrospray-mass spectrometry.

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This document introduces HPLC methods for the analysis of two antihypertensive drugs

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This document describes a new HPLC method for the determination of the tricyclic antidepressant doxepin in 'Aponal 100' tablets. The method uses an extra densely bonded Eclipse XDB-C18 column, which is made with a special Zorbax silica support and designed to reduce or eliminate strong adsorption of basic or acidic compounds. The method is stable at neutral pH and shows excellent and rapid resolution of tricyclic aromatic amines at low buffer concentration. Doxepin is separated from 'Aponal 100' tablets with no interference from excipients.

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A simplified and fast protocol for the analysis of DNA fragmentation during apoptosis

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This paper describes the use of the Agilent 2100 bioanalyzer to analyze the efficiency and kinetics of the cleavage process for the removal of His-tags from recombinant proteins. Data on the processing of 6xHis-tagged GFP (Green Fluorescent Protein) and IL-1β (Interleukin-1 beta) proteins is presented here as part of a comprehensive analysis of the TAGZyme system1.

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This document describes the method of HPLC analysis of glucocorticoids.

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This document describes the results of the separation of quercetin and kaempferol in ginkgo extract and tablets using HPLC.

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This file introduces the application of HPLC in the analysis of water-soluble vitamins.

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The document describes the analysis of tricyclic antidepressant drugs. Tricyclic antidepressants are tricyclic derivatives of diphenylamine or diphenylmethane and have mood-enhancing effects. Antidepressants inhibit the mechanism that inactivates these amines, resulting in a higher concentration at the corresponding receptors. They have parasympatholytic side effects that occur a few days after treatment. The desired antidepressant effects occur after two to three weeks.

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The document describes the HPLC analysis method for quinine and quinidine in cinchona bark extract. The cinchona bark contains 4-12% alkaloids, mainly the diastereomers quinine/quinidine and cinchonine/cinchonidine. Quinine is the major compound accounting for 80% of the total alkaloids in cinchona bark. It is a strong protoplasmic poison with effects on almost any cell. Quinine is used as an anti-malaria medicine. Some soft drinks, such as tonic water, contain up to 80 mg/l of quinine, which gives them a bitter taste.

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This document introduces the application of HPLC technology in the analysis of hypnotic drugs, including separation methods, instrument conditions, etc.

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The document describes two antihypertensive drugs: captopril and enalapril. They lower blood pressure by inhibiting the enzyme that converts angiotensin I into angiotensin II. The document also provides a method for analyzing these two drugs using high-performance liquid chromatography.

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This document introduces the HPLC analysis method for androgen drugs

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This document describes the analysis method for rhein and emodin in rhubarb root extract. The extract has a gentle laxative effect by stimulating the secretion of bile into the intestines and expelling toxic waste matter through the gall duct, thereby cleansing the liver and relieving chronic liver problems.

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This document introduces a HPLC method for the determination of atropine in Belladonna extract.

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This document introduces the mass analysis principles and features of the 5973N high resolution mass spectrometer, including electron bombardment ionization and chemical ionization.

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Agilent CombiZorb scavengers are used to remove unwanted components from combinatorial chemistry reaction mixtures.

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This document describes the features and characteristics of Agilent CombiZorb Scavengers, including non-swelling, broad solvent compatibility, no metal content, and no static electricity.

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