The LTC®2499 is a 16-channel (eight differential), 24-bit, No Latency DSTM ADC with Easy Drive technology and a 2-wire, I2C interface. The patented sampling scheme elimi- nates dynamic input current errors and the shortcomings of on-chip buffering through automatic cancellation of differential input current. This allows large external source impedances and rail-to-rail input signals to be directly digitized while maintaining exceptional DC accuracy. The LTC2499 includes a high accuracy, temperature sensor and an integrated oscillator. This device can be configured to measure an external signal (from combi- nations of 16 analog input channels operating in single- ended or differential modes) or its internal temperature sensor. The integrated temperature sensor offers 1/30th °C resolution and 2°C absolute accuracy. The LTC2499 allows a wide common mode input range (0V to VCC), independent of the reference voltage. Any combination of single-ended or differential inputs can be selected and the first conversion, after a new channel is selected, is valid. Access to the multiplexer output en- ables optional external amplifiers to be shared between all analog inputs and auto calibration continuously removes their associated offset and drift.