Agilent AMDIS Technical Note

About this manual

The document describes the Automated Mass Spectrometry Deconvolution and Identification System (AMDIS), a program developed at the National Institute of Standards and Technology. AMDIS deconvolutes impure mass spectra resulting from coelutions or background contaminants in GC/MSD and LC/MSD data to display reconstructed chromatograms.

What's inside

• Overview
• Pure Spectra from Mixtures
• Mass Spectra Plus Retention-Time Information
• The Origin of AMDIS
• To Obtain AMDIS

Frequently asked questions

What types of mass spectra can the AMDIS system deconvolute?

The system deconvolutes impure GC/MSD and LC/MSD mass spectra that result from coelutions or background contaminants.

What applications are supported by the individual target libraries provided with AMDIS?

The libraries are provided for use in environmental, drugs-of-abuse, toxicological, and flavor/fragrance applications.

How many data files was AMDIS tested against to verify its claim of no false-positive identifications?

The program has been tested on over 30,000 data files against a library of potential Chemical Warfare agents.