Agilent RapidFire High-throughput MS System Troubleshooting Guide

About this manual

This document serves as a troubleshooting guide for the Agilent RapidFire High-throughput MS System. It instructs users to understand and interpret specific flowpath diagrams to diagnose and resolve common operational issues. The guide covers a range of symptoms, from the system failing to sip liquid to specific pump overpressure conditions and mechanical failures like a crashed sipper guide needle.

What's inside

• Understand and interpret the flowpath diagrams
• Symptom 1. The RapidFire system does not seem to be sipping
• Symptom 2. The sip sensor does not detect liquid sample
• Symptom 3. A pump is experiencing Underpressure
• Symptom 4. The mass spectrometer signal is very low
• Symptom 5. A valve port or groove is clogged
• Symptom 6. Pump 1 is overpressuring
• Symptom 7. Pump 2 is overpressuring
• Symptom 8. Pump 3 is overpressuring
• Symptom 9. The sipper guide needle crashed into the plate

Frequently asked questions

What is the normal aspiration time range for the RapidFire system?

The normal range for aspirating 1 mL of water is 25-45 seconds.

What vacuum pressure range should be displayed on the RapidFire UI?

The vacuum pressure displayed on the RapidFire UI should be in the range of -60 to -70 kPa.