Agilent ZORBAX Column Selection Guide for Analytical HPLC

This document introduces the features and characteristics of Agilent ZORBAX HPLC columns, including resolution, column life, and usage methods.


Agilent ZORBAX Column Selection Guide for Analytical HPLC - cover page
Brand
Agilent
Category
Other
Document type
Product Leaflet
Language
English
Pages
35
File format
PDF
File size
9.4 MB
Published
04 July, 2012
Updated
30 September, 2023
MD5 checksum
3CDBB1CF36CE920AA26B19FF87A019BC

About this manual

This document serves as a selection guide for Agilent ZORBAX columns designed for analytical HPLC applications. It details the unique ZORBAX Silica manufacturing process, specifically the Rx-SIL technology, which provides high purity, strength, and controlled pore size to ensure resolution that lasts. The guide explains how these silica characteristics improve chromatographic performance by reducing peak tailing and increasing column durability under high pressure.

What's inside

  • ZORBAX Silica
  • ZORBAX Rx-SIL
  • ZORBAX StableBond
  • ZORBAX Eclipse XDB
  • ZORBAX Bonus-RP
  • ZORBAX Extend-C18
  • ZORBAX High-Throughput
  • ZORBAX LC/MS
  • MicroBore and Capillary Columns
  • ZORBAX Wide-Pore

Specifications

Silica Purity99.995%
Maximum Operating Pressure8000 psi
Column Bed Stability Pressure5000 psi
pH Range for StableBond1 - 6
pH Range for Eclipse XDB2 - 9
pH Range for Extend-C18up to pH 11.5

Frequently asked questions

What is the primary benefit of ZORBAX Rx-SIL silica?

It provides ultra-pure particles with low metal content and low acidity, which reduces peak tailing and improves chromatographic results.

How does ZORBAX StableBond differ from other columns?

It uses bulky, patented silanes to sterically protect the siloxane bond, providing extraordinary chemical and temperature stability in the pH 1-6 range.

What makes ZORBAX Extend-C18 suitable for high pH applications?

It incorporates a unique, patented bidentate silane combined with a double-endcapping process that protects the silica from dissolution at high pH.

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