The Agilent RapidFire 360 High-throughput Mass Spectrometry system is an innovative integrated technology that combines the accurate mass capabilities of time-of-flight (TOF) mass spectrometry with the high-throughput processing speeds of the Agilent High-throughput RapidFire technology, and thereby revolutionizes in vitro ADME analysis.
The Agilent RapidFire 360 High-throughput Mass Spectrometry System is designed to streamline workflows and eliminate bottlenecks in in vitro ADME analysis. It combines the accurate mass capabilities of time-of-flight (TOF) mass spectrometry with high-throughput processing speeds, allowing a 96-well plate to be processed in about 15 minutes without compromising data quality.
The system features seamless integration with Agilent's Mass Hunter software and RapidFire Integrator for efficient data handling. It requires no up-front sample preparation, sampling directly from quenched assay plates. Key capabilities include unattended 24-hour operation, automated cartridge packing, and integrated optical sensors to detect fluid flow aberrations.
| Sample processing time per plate | about 15 minutes for a 96 well plate |
|---|---|
| Single sample processing time | six to ten seconds |
| 384 well plate read time | under 40 minutes |
| Sample preparation requirement | No up-front sample preparation required |
No, the system samples directly from quenched assay plates without the need for offline solid phase extraction or other preprocessing.
Each sample is processed in just six to ten seconds.
A single 384 well plate can be read in under 40 minutes.
Yes, the system enables unattended, 24-hour operation.