Agilent G3793AA MassHunter Optimizer is an automated MS method development software for MRM mode (multiple reaction monitoring) on a triple quad mass spectrometer instrument. It can automatically optimize data acquisition parameters, select best precursor ions, optimize the fragmentor voltage for each precursor ion, select the best fragment ions and optimize collision energy values for each transition.
The document is a Quick Start Guide for the Agilent G3793AA MassHunter Optimizer, an automated software tool designed for multiple-reaction monitoring (MRM) mode optimization on triple quadrupole instruments. It details how to install the software and manage service packs, distinguishing between versions for small molecules and peptides.
It automates the selection of best precursor ions, optimization of fragmentor voltage, selection of best fragment ions, and optimization of collision energy values.
Two versions are installed: one for small molecules and one for peptides.
You can use the Tools menu to update retention times from Acquisition methods.