The Abbott ARCHITECT Syphilis TP assay is a qualitative chemiluminescent microparticle immunoassay for detecting Treponema pallidum antibodies in serum and…
The ARCHITECT Syphilis TP assay is a qualitative CMIA used to detect IgG and IgM antibodies against Treponema pallidum in human serum and plasma. It can be employed as an initial diagnostic test or in conjunction with a nontreponemal test to aid syphilis diagnosis.\n\nKey features include automated testing that reduces manual RPR labor, objective result interpretation, and a three‑antigen (Tp15, Tp17, Tp47) microparticle format. The assay delivers up to 200 results per hour with a first‑result time of 29 minutes, and reagents remain stable for 30 days on‑board.
| Method | Two-step chemiluminescent microparticle immunoassay (CMIA) |
|---|---|
| Throughput | Up to 200 tests per hour |
| Time to first result | 29 minutes |
| Reagent stability (on‑board) | 30 days |
| Calibration stability | 30 days |
| Sample type | Human serum and plasma |
| Result interpretation cutoff | Reactive ≥1.00, Nonreactive <1.00 |
It is a qualitative chemiluminescent microparticle immunoassay for detecting IgG and IgM antibodies against Treponema pallidum in human serum and plasma, used as an initial diagnostic test or together with a nontreponemal test.
The system can process up to 200 tests per hour.
A single test requires 150 µL of serum or plasma.
Results are reactive when the signal is ≥1.00 and nonreactive when it is <1.00.