This document describes a method for transferring methods to the Agilent 1290 Infinity LC system using the Agilent Intelligent System Emulation Technology (ISET). ISET can be used to transfer methods between the Agilent 1100 series quaternary LC systems and the Agilent 1290 Infinity LC systems, which have different mixing characteristics and larger delay volumes. By using ISET, almost identical retention times and separation efficiencies can be achieved.
Agilent Technologies presents a technical overview of Intelligent System Emulation Technology (ISET), a feature of the Agilent 1290 Infinity LC system. ISET allows for seamless method transfer from traditional liquid chromatography systems, such as the Agilent 1100 Series Quantitative LC, to the 1290 Infinity LC system. By enabling this function, users can achieve retention times and resolution that closely match the original data without needing extensive re-validation or adding delay volumes. This manual is written in Japanese.