CHIRALCEL® OD-H column is a chiral stationary phase column, which can be used to analyze chiral compounds such as drugs, pesticides, fragrances, etc. The column surface is coated with cellulose-tri[3,5-dimethoxyphenylcarbamate], and the mobile phase can be used with hexane/isopropanol, ethanol, methanol, methanol/acetonitrile, etc. The column can be used to prepare analytical columns and semi-preparative columns.
This manual describes the CHIRALCEL OD‑H chiral column, its packing material, and the recommended operating conditions. It includes dimensions, pressure limits, flow‑rate ranges, and suitable mobile‑phase compositions for both normal‑phase and polar‑phase separations.
Guidelines for column care are also provided, such as flushing procedures before first use, recommended preservation solvent (90:10 n‑hexane/isopropanol), and cleaning steps after each run. The document emphasizes staying within pressure and flow‑rate limits to extend column lifetime. This manual is written in Chinese.
| Column dimensions (150 mm length) | 4.6 mm ID |
|---|---|
| Maximum operating pressure | 100 Bar (≈1400 psi) |
| Typical maximum flow rate (150 × 4.6 mm) | 1.5 mL/min |
| Preservation solvent composition | 90:10 n‑hexane/isopropanol (v/v) |
| Ideal pressure for longest column life | < 50 Bar |
Use a mixture of n‑hexane and isopropanol in a 90:10 v/v ratio as the preservation solvent.
Pressures below 50 Bar are ideal for longest life, but the column remains safe up to 100 Bar.
Before the first use, flush the column with at least 10 column volumes of ethanol (or the appropriate solvent).