Instructions for use, dosage, warnings and safety information for Janssen's Esketamine Hydrochloride Nasal Spray.
This leaflet provides detailed information on Esketamine Hydrochloride Nasal Spray, including its approved indication for adult depression with acute suicidal ideation, recommended dosing schedule, and administration procedure. It emphasizes that the product must be used only under direct medical supervision in a healthcare setting.
Key safety warnings cover risks of sedation, dissociation, abuse, and suicidal thoughts. The document also outlines contraindications, adverse reactions, storage conditions, packaging details, and regulatory identifiers for the product. This manual is written in Chinese.
| Molecular formula | C13H16ClNO·HCl |
|---|---|
| Molecular weight | 274.2 |
| Spray volume per dose | 0.2 ml (28 mg per spray) |
| Recommended weekly dose | 84 mg (two sprays) for 4 weeks, may reduce to 56 mg |
The recommended dose is 84 mg per week (two sprays) for four weeks, with the possibility to reduce to 56 mg per week based on tolerability.
Store in a sealed container at temperatures not exceeding 30 °C; do not refrigerate or freeze.