This package insert provides usage instructions, dosage adjustments, and safety information for Irinotecan Hydrochloride Injection used to treat advanced…
This document is a package insert for Irinotecan Hydrochloride Injection, a chemotherapy medication indicated for the treatment of advanced colorectal cancer. It details the drug's composition, physical characteristics, and specific indications for use in combination with 5-fluorouracil and leucovorin, or as a single agent for patients who have failed prior chemotherapy. This manual is written in Chinese.
| Molecular Weight | 623.15 |
|---|---|
| Dosage Form | Injection |
| Concentration (Option 1) | 40mg/2ml |
| Concentration (Option 2) | 100mg/5ml |
Irinotecan is administered at 180mg/m2 via intravenous infusion over 30-90 minutes on day 1.
A lower initial dose is recommended for patients over 65 years old based on clinical drug toxicity experience.
No, the use of this drug is not recommended for dialysis patients, and renal function must be monitored closely.