This document provides an overview of ionization theory, API-MS hardware, considerations for samples and solutions, interpretation of API-MS mass spectra, generation of structural information, inlet considerations, troubleshooting, and methods development. The course is designed for undergraduate chemistry students with experience in mass spectrometry, including mass spectrometer operation and EI data interpretation. It is also suitable for LC/MS operators or supervisors planning to use LC/MS, GC/MS operators or supervisors planning to utilize LC/MS, and individuals experienced in LC separations who plan to use MS detection. The course includes practical exercises in API-LC/MS methods development and spectral interpretation.
The document describes an Agilent Chemical Analysis Training Course focused on Atmospheric Pressure Ionization-Liquid Chromatography/Mass Spectrometry (API-LC/MS). It is designed as a one-day lecture-only session intended to demonstrate how API-LC/MS analyses can solve real-world problems in biochemistry, pharmaceutical, clinical, and environmental industries.
API-LC/MS analyses can solve real-world problems in the biochemistry, pharmaceutical, clinical, and environmental industries.
This course features exercises in API-LC/MS methods development and spectral interpretation.