The document introduces the stability of short chain bonded phases, including stability test methods, test results and conclusions.
The document discusses the superior stability of sterically protected short-chain bonded phases, such as CN and C8, compared to standard chromatographic packings. It notes that these StableBond columns provide ideal alternatives to C-18 columns for stable reversed-phase method development.
A graph illustrates column volume data for various stationary phases including Si(-Pr)2C8, Si-(Me)2PrCN, FF, and C8 under specific testing conditions.
The stability testing was performed using columns that are 4.6 x 150 mm.
The stability testing for these columns lasted for 96 hours.