This document introduces the application and advantages of Agilent Technologies' Agilent Multimode Inlet (MMI) for large volume injection (LVI). The LVI method allows for increased sample injection volume, improved analysis results, and reduced solvent usage. Additionally, the LVI process can be automated for higher reproducibility.
The document serves as a tutorial for the Agilent Multimode Inlet (MMI). It introduces Large Volume Injection (LVI) methods to improve analytical sensitivity by injecting larger sample volumes compared to traditional methods. The text explains that LVI allows researchers to increase sample mass reaching the detector, thereby improving signal-to-noise ratios and lowering detection limits.
The guide details three specific operating modes supported by the MMI: Hot Splitless, Cold Splitless, and Solvent Vent. It describes the operational principles of each mode, including temperature programming requirements and liner interactions. The document concludes with a step-by-step tutorial demonstration using an FID MDL check-out sample to illustrate method development. This manual is written in Japanese.
The Large Volume Injection (LVI) method can be applied to injection volumes ranging from a few microliters up to more than 1 milliliter.
The tutorial specifies using an HP-5 column with dimensions of 30 m x 0.32 mm x 0.25 um.
The inlet temperature must be set to 250 ?C during the initial splitless analysis step.