Agilent K45_Learnings from the modulation of methane in GCxGC with flow modulator Manual

Update: 30 September, 2023

This document describes some of the lessons learned from using a flow modulator to modulate methane and points out some common erroneous assumptions, such as that stationary phase bleed is a good indicator of hold-up time. When using this approach to perform fundamental retention studies, one cannot escape the fundamental pitfalls of capillary chromatography. Loss of He through fused-silica at high temperatures and low flows can cause significant errors.

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Publication date: 05 July, 2012

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PDF Link: Agilent K45_Learnings from the modulation of methane in GCxGC with flow modulator Manual PDF