Agilent Real-time Gas Control Overcomes Solvent Gradient Effects Manual

Update: 30 September, 2023

Varian 380-LC series is a range of advanced evaporative light scattering detectors from Polymer Laboratories, now a part of Varian, Inc. The Varian 385-LC delivers sub-ambient evaporation down to 10 °C, providing maximum sensitivity for compounds with significant volatility below ambient temperature. The Varian 380-LC is the instrument of choice for non-volatile compounds, where temperatures of 100 °C or above are required. Both instruments benefit from fast data output rates and extremely low dispersion for fast LC, and deliver a universal response down to the low nanogram range for truly representative analysis. Repeatability is less than 2% for improved consistency of results. Real-time gas control eliminates solvent effects to provide a constant response across a gradient. Control and digital data collection come as standard for multi-vendor platforms and so there is no need for an analog to digital converter. On-the-fly adjustment of light source intensity also saves time during a run, too - all in the smallest footprint around. Being complementary to LC/MS, and offering unrivalled flexibility and sensitivity, the Varian 380-LC series are the ELSDs of choice for the most demanding applications.


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Publication date: 05 July, 2012

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