Agilent Technologies Effect of Mobile-Phase Ionic Strength on Neutral Strongly Basic Antibodies at pH 7.0

Update: 29 September, 2023

This document investigates the effect of mobile-phase ionic strength on neutral and strongly basic antibodies. The results show that strongly basic molecules interact with silica-based column packings to a much greater extent than neutral molecules. Additionally, the concentration of phosphate buffer has an impact on peak shape and retention time.

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MD5 Checksum: 6DADA30346E2CBA7E0D2D574C6897D4F

Publication date: 03 July, 2012

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PDF Link: Agilent Technologies Effect of Mobile-Phase Ionic Strength on Neutral Strongly Basic Antibodies at pH 7.0 PDF