Agilent Oligonucleotides Fraction Collection from Capillary Gel Electrophoresis Offline MALDI-TOF

Update: 28 September, 2023

This document describes the collection of fractions from an oligonucleotide separation using gel electrophoresis and offline MALDI-TOF analysis. By using the Agilent oligonucleotide kit and Agilent Capillary Electrophoresis system, antisense oligonucleotides can be successfully separated. The Agilent ChemStation software allows for fully automated collection of fractions using signal A as the peak sensor. This method enables further analysis of the separated peaks and determination of the molecular mass.

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Publication date: 03 July, 2012

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