Agilent Comparison of ZORBAX Poroshell 300Extend-C18 Totally Porous Packing in Achieving Very Rapid High-pH Separation of Proteins
Update: 30 September, 2023
The document introduces the advantages of ZORBAX Poroshell packings in the HPLC separation of large molecules such as proteins. This surface porous particle can make the separation faster. At high pH, peptides and small proteins can also be separated by using Extend-C18-bonded Poroshell particles. The high pH may be desirable for improving selectivity, solubility, ease of downstream processing, or to change signal-to-noise and charge-state in LC/MS. By extending the gradient time, it is possible to achieve even higher resolution in typical run times of 10 to 20 min.
Brand: Agilent
File format: PDF
Size: 446 KB
MD5 Checksum: 504176B0EE2D5C7BE024E1E96EF84827
Publication date: 02 July, 2012
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