Agilent Technologies Optimization of the Rapid HPLC Analysis of Monoclonal Intact Antibodies Light Chains Heavy Chains Using ZORBAX Poroshell Columns
Update: 28 September, 2023
This document discusses the advantages of high-resolution analysis of intact antibodies, heavy chains, and light chains using ZORBAX Poroshell technology for high-velocity gradient separations. Method development is significantly improved with ZORBAX Poroshell HPLC columns, achieving up to 90% reduction in analysis time. ZORBAX Poroshell 300SB columns are available in various internal diameters and bonded phases for optimal sensitivity, resolution, and speed. The use of an HPLC instrument optimized for low-volume peaks of narrow width maximizes ZORBAX Poroshell resolution. The document also addresses the challenges in monoclonal antibody analysis.
Brand: Agilent
File format: PDF
Size: 501 KB
MD5 Checksum: 00B8ED9FCAE4A6CAB844AF1ECF6E8A9D
Publication date: 02 July, 2012
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