Update: 29 September, 2023
The document introduces the Agilent Technologies' Multiple Affinity Removal System, which combines the specificity of antibody-antigen recognition with the efficiency of standard liquid chromatography instrumentation. This system effectively removes multiple proteins from human serum, including albumin, transferrin, IgG, IgA, haptoglobin, and antitrypsin, in a single step with high specificity and reproducibility. The document also demonstrates several methods to optimize column binding capacities, such as coupling two identical columns to increase capacity, using a custom column with dimensions of 10x100mm to enhance capacity, and achieving optimal binding capacity by injecting samples at a low flow rate.
File format: PDF
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MD5 Checksum: 874C9823E5CFDB876BE269A6FD2EF905
Publication date: 02 July, 2012
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PDF Link: Agilent Binding Capacity Assessment Optimization for the Multiple Affinity Removal System PDF