Update: 30 September, 2023
This application note describes the characterization of a monoclonal antibody at low nanogram levels using an Agilent HPLC-Chip system coupled to an Agilent Accurate-Mass Q-TOF MS instrument. The superior sensitivity and mass accuracy of the HPLC-Chip LC/MS platform, combined with the powerful data processing capabilities of Agilent MassHunter and BioConfirm software, enabled easy and rapid identifi cation of antibody heterogeneity and cleaved fragments. Robust, reliable, and easy to use, Agilent nanofl ow LC/MS technology is ideally suited for the routine analysis of biopharmaceuticals.
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MD5 Checksum: C2392DE2466A496858D18AA189E3D617
Publication date: 02 July, 2012
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